Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

Thousands of new genes are hidden inside the “dark matter” of our genome. Previously thought to be noise left over from evolution, a new study found that some of these tiny DNA snippets can make ...

A comprehensive encyclopedia of the known functions of all protein-coding human genes has just been completed and released. Researchers used large-scale evolutionary modeling to integrate data on ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...