Background Despite considerable interest, the population-based frequency, clinical characteristics and natural history of cognitive impairment in amyotrophic lateral sclerosis (ALS) are not known.

a Department of Medical Sciences, Section of Neurology, Università del Piemonte Orientale “A Avogadro”, Novara, Italy, b Clinica Neurologica, Ospedale Maggiore, Corso Mazzini 18, 28100 Novara, Italy ...

Dr F X Glocker, Department of Neurology, University of Freiburg, Breisacher Straße 64, D-79106 Freiburg, Germany. Telephone 0049 761 270 5313; fax 0049 761 270 5313. OBJECTIVE Vitamin B 12 deficiency ...

Objectives We aimed to identify existing outcome measures for functional neurological disorder (FND), to inform the development of recommendations and to guide future research on FND outcomes. Methods ...

OBJECTIVES Increased resistance to stretch of muscles after stroke may be the result of centrally mediated neural factors such as spasticity or local, peripheral factors such as muscle contracture or ...

4 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden Background Alzheimer's disease (AD) ...

2 NIHR Biomedical Research Centre, Guy's & St. Thomas’ NHS Foundation Trust and King's College London, London, UK 3 Farr Institute of Health Informatics, University College London, London, UK 4 ...

Background High-efficacy disease-modifying therapies (HETs) have substantially improved multiple sclerosis (MS) management, yet ongoing cognitive decline remains a concern. This study aims to assess ...

Background In the presence of neurological insult, how language and memory networks jointly reorganise provides insights into mechanisms of neuroplasticity and can inform presurgical planning. As ...

Correspondence to Prof Bart C Jacobs, Departments of Neurology and Immunology, Erasmus MC, P.O. Box 2040, Rotterdam 3000 CA, The Netherlands; b.jacobs{at}erasmusmc.nl Guillain-Barré syndrome (GBS) is ...

University of Iowa, The Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA Objective: The objective of the Predict-HD study is to use genetic, neurobiological and refined clinical ...

Background Limited data are available on the global rates of paediatric multiple sclerosis. Here, we report on the estimated worldwide prevalence of paediatric MS. Methods We included paediatric ...