Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a …

Letrozole is recommended as the first-line medication for ovulation induction in polycystic ovary syndrome. Compared to clomiphene (Clomid), it causes higher number of ovulation and live birth rates.

Mechanism of action. Letrozole acts locally on aromatase enzyme and blocks conversion of androgen to estrogen in ovarian follicle, peripheral tissue, and the brain.

Dec 1, 2022 · Letrozole is a powerful endocrine medication that targets and inhibits the aromatase, often known as an aromatase inhibitor (AI). It aids in the adjuvant, neoadjuvant, and metastatic treatment …

Letrozole is a type of drug called an aromatase inhibitor. It blocks aromatase so that it can't change androgens into oestrogen. How do you have letrozole? Letrozole is a tablet. You must take tablets …

Aug 19, 2024 · Letrozole belongs to a class of medicines called aromatase inhibitors. It works by blocking an enzyme called aromatase that helps produce estrogen in the body. By lowering the …

Modern third-generation aromatase inhibitors (AIs) effectively block the production of estrogen without exerting effects on other steroidogenic pathways. The discovery of letrozole (Femara1) achieved the …

Nov 21, 2023 · Mechanism of action Letrozole, primarily used in the treatment of hormone-responsive breast cancer, functions as a potent inhibitor of aromatase, an enzyme that catalyzes the …

Mechanism of Action: Letrozole effectively inhibits the aromatase enzyme, leading to decreased estrogen production, which is fundamental in hormone-sensitive cancers.

May 13, 2021 · Mechanism of Action: Decreases estrogen biosynthesis by selective competitive inhibition of aromatase in peripheral tissues (estrogen synthetase) Inhibition of aromatase reduces …