The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca 2+ ion channel found in neurons. [3][4] The NMDA receptor is one of …

Dec 11, 2022 · The N-methyl-D-aspartate (NMDA) receptor is a glutamate receptor, the human brain's primary excitatory neurotransmitter. It plays an integral role in synaptic plasticity, a neuronal …

Jul 19, 2025 · NMDA drugs are substances that interact with N-methyl-D-aspartate receptors in the brain, modifying the flow of information between nerve cells. This action influences a wide range of …

Nov 24, 2024 · NMDA receptors belong to the family of ionotropic glutamate receptors, distinct from G protein-coupled receptors (GPCRs). These receptors play a pivotal role in regulating various …

Here, we will review the relationship between NMDA receptor structure and function, the diversity and significance of NMDA receptor subtypes in the CNS, as well as principles and rules by which NMDA …

NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N -Methyl- D -aspartate receptor (NMDAR). They are commonly used as anesthetics for humans and …

N-methyl-D-aspartate (NMDA) receptors are a subtype of ionotropic glutamate receptors and represent a major class of excitatory neurotransmitter receptors in the central nervous system (CNS).

Aug 4, 2025 · Among these are NMDA receptors, embedded within the membranes of nerve cells. These receptors play a central role in how our brains process information and adapt to new …

Aug 2, 2023 · Here, we review newly discovered dimensions of postsynaptic NMDAR signaling supporting neural plasticity and cognition, such as the nanoscale organization of NMDAR complexes, …

Jun 18, 2025 · NMDA receptors are a subtype of glutamate receptor widespread throughout the central nervous system. They regulate the strength of connections between neurons, a process known as …